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The antibody against IMMP2L was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 38-175 of human IMMP2L(NP_001231535.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against IMMP2L was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 38-175 of human IMMP2L(NP_001231535.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01208A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IMMP2L |
| Target Synonyms | IMMP2L; IMMP2L-IT1; IMP2; IMP2-LIKE; mitochondrial inner membrane protease subunit 2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, U-251 MG | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 38-175 of human IMMP2L(NP_001231535.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TFLDRVACVARVEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE | Uniprot ID | Q96T52 |
Uniprot Id
Q96T52
Target Species
Human
Target Name
IMMP2L
Target Full Name
Mitochondrial inner membrane protease subunit 2
Target Function
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
Target Involvement
Gilles de la Tourette syndrome (GTS)
Target Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Target Protein Families
Peptidase S26 family, IMP2 subfamily
Target Tissue Specificity
Expressed in all tissues tested except adult liver and lung.
Target Synonyms
IMMP2L; Mitochondrial inner membrane protease subunit 2; IMP2-like protein
Target Background
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene.
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