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The antibody against INTS4 was raised in rabbit using the Human INTS4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against INTS4 was raised in rabbit using the Human INTS4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48229A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INTS4 |
| Target Synonyms | Int4 antibody; INT4_HUMAN antibody; Integrator complex subunit 4 antibody; ints4 antibody; MGC16733 antibody; MST093 antibody; MSTP093 antibody; RGD1305036 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human INTS4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96HW7 |
Uniprot Id
Q96HW7
Target Species
Human
Target Name
INTS4
Target Full Name
Integrator complex subunit 4
Target Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
Target Subcellular Location
Nucleus.
Target Protein Families
Integrator subunit 4 family
Target Synonyms
Int4; INT4_HUMAN; Integrator complex subunit 4; ints4; MGC16733; MST093; MSTP093; RGD1305036
Target Background
INTS4 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
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