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Rabbit anti-Human IQGAP2 Polyclonal Antibody

The antibody against IQGAP2 was raised in rabbit using the Synthetic peptide of Human IQGAP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-28271A

The antibody against IQGAP2 was raised in rabbit using the Synthetic peptide of Human IQGAP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-28271A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIQGAP2
Target SynonymsIQ motif containing GTPase activating protein 2 antibody; IQGA2_HUMAN antibody; Iqgap2 antibody; Ras GTPase activating-like protein antibody; Ras GTPase-activating-like protein IQGAP2 antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human IQGAP2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ13576
Background Information
  • Uniprot Id

    Q13576

  • Target Species

    Human

  • Target Name

    IQGAP2

  • Target Full Name

    Ras GTPase-activating-like protein IQGAP2

  • Target Function

    Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin.

  • Target Tissue Specificity

    Isoform 2 expression is enhanced in testis.

  • Target Synonyms

    IQ motif containing GTPase activating protein 2; IQGA2_HUMAN; Iqgap2; Ras GTPase activating-like protein; Ras GTPase-activating-like protein IQGAP2

  • Target Background

    This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.

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