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The antibody against IRGM was raised in rabbit using the Recombinant Human Immunity-related GTPase family M protein (1-181AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against IRGM was raised in rabbit using the Recombinant Human Immunity-related GTPase family M protein (1-181AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-40326A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRGM |
| Target Synonyms | IFI1 antibody; Iigp3 antibody; Iipg3 antibody; Immunity related GTPase family M protein 1 antibody; Immunity related GTPase family | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Immunity-related GTPase family M protein (1-181AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A1A4Y4 |
Uniprot Id
A1A4Y4
Target Species
Human
Target Name
IRGM
Target Full Name
Immunity-related GTPase family M protein
Target Function
Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility.
Target Involvement
Inflammatory bowel disease 19 (IBD19)
Target Subcellular Location
Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Cell projection, phagocytic cup.
Target Protein Families
TRAFAC class dynamin-like GTPase superfamily, IRG family
Target Tissue Specificity
Widely expressed (at protein level). Expressed in several tissues including colon, small bowel and peripheral blood leukocytes.
Target Research Area
Immunology
Target Synonyms
IFI1; Iigp3; Iipg3; Immunity related GTPase family M protein 1; Immunity related GTPase family, M; Immunity-related GTPase family M protein 1; Immunity-related GTPase family M protein; Interferon inducible protein 1; Interferon-inducible protein 1; Irgm; IRGM_HUMAN; IRGM1; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG 47; LRG-47; LRG-47-like protein; LRG47; MGC149263; MGC149264
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