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The antibody against ITPR3 was raised in rabbit using the Synthetic peptide of Human ITPR3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ITPR3 was raised in rabbit using the Synthetic peptide of Human ITPR3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ITPR3 Antibody(ITPR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ITPR3 Antibody(ITPR3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)2
| Cat.No | ADC-26515A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ITPR3 |
| Target Synonyms | 4, 4 antibody; 5-trisphosphate receptor antibody; 5-trisphosphate receptor type 3 antibody; FLJ36205 antibody; Inositol 1 antibody; Inositol 1, 5 trisphosphate receptor antibody; Type 3 InsP3 receptor antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human ITPR3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14573 |
Uniprot Id
Q14573
Target Species
Human
Target Name
ITPR3
Target Full Name
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3
Target Function
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
InsP3 receptor family
Target Tissue Specificity
Expressed in intestinal crypt and villus epithelial cells.
Target Synonyms
4; 5-trisphosphate receptor; 5-trisphosphate receptor type 3; FLJ36205; Inositol 1; Inositol 1,4,5 trisphosphate receptor type 3; InsP3R3; IP3 receptor; IP3 receptor isoform 3; IP3R 3; IP3R; IP3R3; ITPR 3; ITPR3; ITPR3_HUMAN; Type 3 inositol 1; Type 3 inositol 1,4,5 trisphosphate receptor; Type 3 InsP3 receptor
Target Background
This gene encodes a receptor for inositol 1, 4, 5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1, 4, 5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
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