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Rabbit anti-Human JAG2 Polyclonal Antibody

The antibody against JAG2 was raised in rabbit using the Synthetic peptide of Human JAG2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-26511A

The antibody against JAG2 was raised in rabbit using the Synthetic peptide of Human JAG2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-26511A ClonalityPolyclonal
Host SpeciesRabbitTarget NameJAG2
Target SynonymsJAG2 antibody; Protein jagged-2 antibody; Jagged2 antibody; hJ2 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human JAG2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y219
Background Information
  • Uniprot Id

    Q9Y219

  • Target Species

    Human

  • Target Name

    JAG2

  • Target Full Name

    Protein jagged-2

  • Target Function

    Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Tissue Specificity

    Expressed in heart, placenta and skeletal muscle and to a lesser extent in pancreas. Very low expression in brain, lung, liver and kidney.

  • Target Synonyms

    HJ2; SER2; LGMDR27; JAG2

  • Target Background

    The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

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