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The antibody against KLK1 was raised in rabbit using the Recombinant Human Kallikrein-1 protein (25-262AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against KLK1 was raised in rabbit using the Recombinant Human Kallikrein-1 protein (25-262AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-49730A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KLK1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kallikrein-1 protein (25-262AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P06870 |
Uniprot Id
P06870
Target Species
Human
Target Name
KLK1
Target Full Name
Kallikrein-1
Target Function
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Target Protein Families
Peptidase S1 family, Kallikrein subfamily
Target Tissue Specificity
Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
Target Research Area
Cancer
Target Synonyms
Glandular kallikrein 1; hK 1; hK1; Kallikrein serine protease 1; Kallikrein-1; Kidney/pancreas/salivary gland kallikrein; Klk 6; KLK1; KLK1_HUMAN; Klk6; KLKR; Tissue kallikrein
Target Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
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