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Rabbit anti-Human LDHB Polyclonal Antibody

The antibody against LDHB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-15949A

The antibody against LDHB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-15949A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLDHB
Target SynonymsLDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281; HBFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293TApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 2-334 of human LDHB (NP_002291.1).Target SpeciesHuman
Uniprot IDP07195Immunogen Sequence
Background Information
  • Uniprot Id

    P07195

  • Target Species

    Human

  • Target Name

    LDHB

  • Target Full Name

    L-lactate dehydrogenase B chain

  • Target Involvement

    Lactate dehydrogenase B deficiency (LDHBD)

  • Target Subcellular Location

    Cytoplasm. Mitochondrion inner membrane; Peripheral membrane protein.

  • Target Protein Families

    LDH/MDH superfamily, LDH family

  • Target Research Area

    Metabolism

  • Target Synonyms

    Epididymis secretory protein Li 281; HEL S 281; L lactate dehydrogenase B chain; L-lactate dehydrogenase B chain; Lactate Dehydrogenase B; Lactate dehydrogenase H chain; LDH B ; LDH H; LDH heart subunit; LDH-B; LDH-H; LDHB; LDHB_HUMAN; LDHBD; LDHH; Renal carcinoma antigen NY REN 46; Renal carcinoma antigen NY-REN-46; TRG-5; TRG5

  • Target Background

    This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

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