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The antibody against LRIG1 was raised in rabbit using the Synthetic peptide of Human LRIG1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against LRIG1 was raised in rabbit using the Synthetic peptide of Human LRIG1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-28215A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LRIG1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human LRIG1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96JA1 |
Uniprot Id
Q96JA1
Target Species
Human
Target Name
LRIG1
Target Full Name
Leucine-rich repeats and immunoglobulin-like domains protein 1
Target Function
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Widely expressed.
Target Synonyms
Leucine rich repeat protein; Leucine rich repeat protein LRIG1; leucine rich repeats and immunoglobulin like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1; LIG 1; LIG-1; LIG1; Lrig1; LRIG1_HUMAN; Ortholog of mouse integral membrane glycoprotein LIG 1
Target Background
Predicted to act upstream of or within several processes, including innervation; otolith morphogenesis; and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space.
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