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Rabbit anti-Human LYPLA2 Polyclonal Antibody

The antibody against LYPLA2 was raised in rabbit using the Recombinant Human Acyl-protein thioesterase 2 protein (1-226AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

ADC-50417A

The antibody against LYPLA2 was raised in rabbit using the Recombinant Human Acyl-protein thioesterase 2 protein (1-226AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.

$299.00

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Specifications


Cat.No ADC-50417A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLYPLA2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IFStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Acyl-protein thioesterase 2 protein (1-226AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO95372
Background Information
  • Uniprot Id

    O95372

  • Target Species

    Human

  • Target Name

    LYPLA2

  • Target Full Name

    Acyl-protein thioesterase 2

  • Target Function

    Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    AB hydrolase superfamily, AB hydrolase 2 family

  • Target Tissue Specificity

    Expressed in various breast cancer cell lines.

  • Target Research Area

    Metabolism

  • Target Synonyms

    Acyl protein thioesterase 2; Acyl protein thioesterase; Acyl-protein thioesterase 2; APT 2; APT-2; APT2; DJ886K2.4; EC 3.1.2.- ; LPL I; LPL II; LPL-II; LYPA2_HUMAN; LYPLA 2; Lypla2; Lysophospholipase II; LysoPLA II; OTTHUMP00000002999; OTTHUMP00000044831

  • Target Background

    Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet.

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