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The antibody against MARCH4 was raised in rabbit using the Synthesized peptide derived from internal of Human MARCH4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.
The antibody against MARCH4 was raised in rabbit using the Synthesized peptide derived from internal of Human MARCH4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.
$297.00
| Cat.No | ADC-41257A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | 4-Mar |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human MARCH4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P2E8 |
Uniprot Id
Q9P2E8
Target Species
Human
Target Name
MARCHF4
Target Full Name
E3 ubiquitin-protein ligase MARCHF4
Target Function
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Target Subcellular Location
Golgi apparatus membrane; Multi-pass membrane protein.
Target Tissue Specificity
Expressed in brain and placenta.
Target Synonyms
MARCHF4; KIAA1399; MARCH4; RNF174; E3 ubiquitin-protein ligase MARCHF4; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; MARCH-IV; RING finger protein 174; RING-type E3 ubiquitin transferase MARCHF4
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