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Rabbit anti-Human MARCH4 Polyclonal Antibody

The antibody against MARCH4 was raised in rabbit using the Synthesized peptide derived from internal of Human MARCH4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.

ADC-41257A

The antibody against MARCH4 was raised in rabbit using the Synthesized peptide derived from internal of Human MARCH4. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC.

$297.00

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Specifications


Cat.No ADC-41257A ClonalityPolyclonal
Host SpeciesRabbitTarget Name4-Mar
FormLiquidSpecies ReactivityHuman, Mouse
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human MARCH4.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9P2E8
Background Information
  • Uniprot Id

    Q9P2E8

  • Target Species

    Human

  • Target Name

    MARCHF4

  • Target Full Name

    E3 ubiquitin-protein ligase MARCHF4

  • Target Function

    E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

  • Target Subcellular Location

    Golgi apparatus membrane; Multi-pass membrane protein.

  • Target Tissue Specificity

    Expressed in brain and placenta.

  • Target Synonyms

    MARCHF4; KIAA1399; MARCH4; RNF174; E3 ubiquitin-protein ligase MARCHF4; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; MARCH-IV; RING finger protein 174; RING-type E3 ubiquitin transferase MARCHF4

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