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The antibody against MED22 was raised in rabbit using the Recombinant Human Mediator of RNA polymerase II transcription subunit 22 protein (2-140AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against MED22 was raised in rabbit using the Recombinant Human Mediator of RNA polymerase II transcription subunit 22 protein (2-140AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
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| Cat.No | ADC-20249A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MED22 |
| Target Synonyms | MED22 antibody; SURF5Mediator of RNA polymerase II transcription subunit 22 antibody; Mediator complex subunit 22 antibody; Surfeit locus protein 5 antibody; Surf-5 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Mediator of RNA polymerase II transcription subunit 22 protein (2-140AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15528 |
Uniprot Id
Q15528
Target Species
Human
Target Name
MED22
Target Full Name
Mediator of RNA polymerase II transcription subunit 22
Target Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Target Subcellular Location
Nucleus.
Target Protein Families
Mediator complex subunit 22 family
Target Synonyms
MED22; SURF5Mediator of RNA polymerase II transcription subunit 22; Mediator complex subunit 22; Surfeit locus protein 5; Surf-5
Target Background
This gene encodes a protein component of the mediator complex, which functions in the regulation of transcription by bridging interactions between gene-specific regulatory factors, RNA polymerase II, and general transcription factors. Alternatively spliced transcript variants encoding different isoforms have been observed.
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