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The antibody against MKL2 was raised in rabbit using the Recombinant Human MKL/myocardin-like protein 2 protein (164-313AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against MKL2 was raised in rabbit using the Recombinant Human MKL/myocardin-like protein 2 protein (164-313AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-04498A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MKL2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human MKL/myocardin-like protein 2 protein (164-313AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9ULH7 |
Uniprot Id
Q9ULH7
Target Species
Human
Target Name
MRTFB
Target Full Name
Myocardin-related transcription factor B
Target Function
Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation.
Target Involvement
A chromosomal aberration involving C11orf95 is found in 3 chondroid lipomas. Translocation t(11;16)(q13;p13) with C11orf95 produces a C11orf95-MKL2 fusion protein (PubMed:20607705).
Target Subcellular Location
Nucleus.
Target Synonyms
FLJ31823; Megakaryoblastic leukemia 2; megakaryoblastic leukemia 2 protein; MKL/myocardin-like 2; MKL/myocardin-like protein 2; Mkl2; MKL2_HUMAN; MRTF-B; Myocardin-related transcription factor B; NPD001
Target Background
Enables transcription coactivator activity. Involved in positive regulation of pri-miRNA transcription by RNA polymerase II and positive regulation of striated muscle tissue development. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
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