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The antibody against MPDZ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1100-1380 of human MPDZ (NP_003820.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MPDZ was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1100-1380 of human MPDZ (NP_003820.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10106A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MPDZ |
| Target Synonyms | HYC2; MUPP1; MPDZ | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, LO2, Mouse brain, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1380 of human MPDZ (NP_003820.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75970 | Immunogen Sequence |
Uniprot Id
O75970
Target Species
Human
Target Name
MPDZ
Target Full Name
Multiple PDZ domain protein
Target Function
Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Promotes clustering of HT2RC at the cell surface.
Target Involvement
Hydrocephalus, non-syndromic, autosomal recessive 2 (HYC2)
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, postsynaptic density. Cell projection, dendrite. Cell junction, tight junction. Cell junction, synapse. Cell junction, synapse, synaptosome.
Target Tissue Specificity
Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
Target Synonyms
MPDZ; MUPP1; Multiple PDZ domain protein; Multi-PDZ domain protein 1
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