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Rabbit anti-Human MPV17 Polyclonal Antibody

The antibody against MPV17 was raised in rabbit using the Recombinant Human Protein Mpv17 protein (1-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

ADC-44841A

The antibody against MPV17 was raised in rabbit using the Recombinant Human Protein Mpv17 protein (1-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

$299.00

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Specifications


Cat.No ADC-44841A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMPV17
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein Mpv17 protein (1-176AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP39210
Background Information
  • Uniprot Id

    P39210

  • Target Species

    Human

  • Target Name

    MPV17

  • Target Full Name

    Mitochondrial inner membrane protein Mpv17

  • Target Function

    Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance. May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation.

  • Target Involvement

    Mitochondrial DNA depletion syndrome 6 (MTDPS6)

  • Target Subcellular Location

    Mitochondrion inner membrane; Multi-pass membrane protein.

  • Target Protein Families

    Peroxisomal membrane protein PXMP2/4 family

  • Target Tissue Specificity

    Ubiquitous. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain and heart.

  • Target Research Area

    Metabolism

  • Target Synonyms

    Glomerulosclerosis; Mpv17; Mpv17 human homolog of glomerulosclerosis and nephrotic syndrome; MpV17 mitochondrial inner membrane protein; MPV17_HUMAN; MTDPS6; Protein Mpv17; SYM1

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