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Rabbit anti-Human MRPL16 Polyclonal Antibody

The antibody against MRPL16 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human MRP-L16. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-38202A

The antibody against MRPL16 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human MRP-L16. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-38202A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL16
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human MRP-L16.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NX20
Background Information
  • Uniprot Id

    Q9NX20

  • Target Species

    Human

  • Target Name

    MRPL16

  • Target Full Name

    Large ribosomal subunit protein uL16m

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Universal ribosomal protein uL16 family

  • Target Synonyms

    39S ribosomal protein L16; 39S ribosomal protein L16 mitochondrial; L16mt; mitochondrial; Mitochondrial ribosomal protein L16; MRP-L16; Mrpl16; PNAS 111; RM16_HUMAN

  • Target Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

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