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Rabbit anti-Human MRPL18 Polyclonal Antibody

The antibody against MRPL18 was raised in rabbit using the Synthesized peptide derived from internal of Human MRPL18. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41573A

The antibody against MRPL18 was raised in rabbit using the Synthesized peptide derived from internal of Human MRPL18. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41573A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMRPL18
FormLiquidSpecies ReactivityHuman
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human MRPL18.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H0U6
Background Information
  • Uniprot Id

    Q9H0U6

  • Target Species

    Human

  • Target Name

    MRPL18

  • Target Full Name

    Large ribosomal subunit protein uL18m

  • Target Function

    Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Universal ribosomal protein uL18 family

  • Target Synonyms

    39S ribosomal protein L18; 39S ribosomal protein L18 mitochondrial ; 39S ribosomal protein L18; mitochondrial precursor; HSPC071; L18mt; mitochondrial; Mitochondrial ribosomal protein L18 ; Mitochondrial ribosomal protein L18 (MRPL18 protein); MRP-L18; Mrpl18; RM18_HUMAN; RP1 195P10.3 001

  • Target Background

    This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16.

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