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The antibody against MRPL18 was raised in rabbit using the Recombinant Human 39S ribosomal protein L18, mitochondrial protein (14-180AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against MRPL18 was raised in rabbit using the Recombinant Human 39S ribosomal protein L18, mitochondrial protein (14-180AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-24404A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL18 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human 39S ribosomal protein L18, mitochondrial protein (14-180AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H0U6 |
Uniprot Id
Q9H0U6
Target Species
Human
Target Name
MRPL18
Target Full Name
Large ribosomal subunit protein uL18m
Target Function
Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Universal ribosomal protein uL18 family
Target Synonyms
39S ribosomal protein L18; 39S ribosomal protein L18 mitochondrial ; 39S ribosomal protein L18; mitochondrial precursor; HSPC071; L18mt; mitochondrial; Mitochondrial ribosomal protein L18 ; Mitochondrial ribosomal protein L18 (MRPL18 protein); MRP-L18; Mrpl18; RM18_HUMAN; RP1 195P10.3 001
Target Background
This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16.
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