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The antibody against MRPL50 was raised in rabbit using the Recombinant Human 39S ribosomal protein L50, mitochondrial protein (1-158AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against MRPL50 was raised in rabbit using the Recombinant Human 39S ribosomal protein L50, mitochondrial protein (1-158AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human lung tissue using MRPL50 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using MRPL50 Antibody at dilution of 1:1002
| Cat.No | ADC-24378A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL50 |
| Target Synonyms | MRPL50 antibody; 39S ribosomal protein L50 antibody; mitochondrial antibody; L50mt antibody; MRP-L50 antibody; Mitochondrial large ribosomal subunit protein mL50 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 39S ribosomal protein L50, mitochondrial protein (1-158AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N5N7 |
Uniprot Id
Q8N5N7
Target Species
Human
Target Name
MRPL50
Target Full Name
Large ribosomal subunit protein mL50
Target Subcellular Location
Mitochondrion.
Target Protein Families
Mitochondrion-specific ribosomal protein mL50 family
Target Synonyms
MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50; Mitochondrial large ribosomal subunit protein mL50
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.
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