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The antibody against NDN was raised in rabbit using the Recombinant Human Necdin protein (1-98AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against NDN was raised in rabbit using the Recombinant Human Necdin protein (1-98AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-05484A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NDN |
| Target Synonyms | HsT16328 antibody; NDN antibody; NECD_HUMAN antibody; Necdin antibody; Necdin homolog antibody; Necdin MAGE family member antibody; necdin related protein antibody; PWCR antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Necdin protein (1-98AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99608 |
Uniprot Id
Q99608
Target Species
Human
Target Name
NDN
Target Full Name
Necdin
Target Function
Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences.
Target Subcellular Location
Perikaryon. Nucleus. Note=Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix.
Target Tissue Specificity
Almost ubiquitous. Detected in fetal brain, lung, liver and kidney; in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Not detected in peripheral blood leuko
Target Synonyms
HsT16328; NDN; NECD_HUMAN; Necdin; Necdin homolog; Necdin MAGE family member; necdin related protein; PWCR
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