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The antibody against NKD1 was raised in rabbit using the Recombinant Human Protein naked cuticle homolog 1 protein (269-384AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against NKD1 was raised in rabbit using the Recombinant Human Protein naked cuticle homolog 1 protein (269-384AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-05505A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NKD1 |
| Target Synonyms | NKD1 antibody; NKD antibody; PP7246 antibody; Protein naked cuticle homolog 1 antibody; Naked-1 antibody; hNkd antibody; hNkd1 antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein naked cuticle homolog 1 protein (269-384AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q969G9 |
Uniprot Id
Q969G9
Target Species
Human
Target Name
NKD1
Target Full Name
Protein naked cuticle homolog 1
Target Function
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
Target Subcellular Location
Cell membrane. Cytoplasm.
Target Protein Families
NKD family
Target Tissue Specificity
Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen.
Target Synonyms
NKD1; NKD; PP7246; Protein naked cuticle homolog 1; Naked-1; hNkd; hNkd1
Target Background
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
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