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Rabbit anti-Human NPTN Polyclonal Antibody

The antibody against NPTN was raised in rabbit using the Recombinant Human Neuroplastin protein (29-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-16769A

The antibody against NPTN was raised in rabbit using the Recombinant Human Neuroplastin protein (29-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-16769A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNPTN
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Neuroplastin protein (29-200AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y639
Background Information
  • Uniprot Id

    Q9Y639

  • Target Species

    Human

  • Target Name

    NPTN

  • Target Full Name

    Neuroplastin

  • Target Function

    Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1; stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell junction, synapse, postsynaptic density.

  • Target Tissue Specificity

    Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level).

  • Target Synonyms

    GP55; GP65; Neuroplastin; np55; np65; Nptn; NPTN_HUMAN; SDFR1; SDR-1; SDR1; stromal cell derived factor receptor 1; Stromal cell-derived receptor 1

  • Target Background

    This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants.

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