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The antibody against NRG2 was raised in rabbit using the Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against NRG2 was raised in rabbit using the Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-24234A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NRG2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14511 |
Uniprot Id
O14511
Target Species
Human
Target Name
NRG2
Target Full Name
Pro-neuregulin-2, membrane-bound isoform
Target Function
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Target Subcellular Location
[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-2]: Secreted.
Target Protein Families
Neuregulin family
Target Tissue Specificity
Restricted to the cerebellum in the adult.
Target Research Area
Neuroscience
Target Synonyms
Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2_HUMAN; NTAK; Pro NRG2; Pro-NRG2
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