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Rabbit anti-Human NRG2 Polyclonal Antibody, HRP conjugated

The antibody against NRG2 was raised in rabbit using the Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-24232A

The antibody against NRG2 was raised in rabbit using the Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-24232A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNRG2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateHRP conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO14511
Background Information
  • Uniprot Id

    O14511

  • Target Species

    Human

  • Target Name

    NRG2

  • Target Full Name

    Pro-neuregulin-2, membrane-bound isoform

  • Target Function

    Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.

  • Target Subcellular Location

    [Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-2]: Secreted.

  • Target Protein Families

    Neuregulin family

  • Target Tissue Specificity

    Restricted to the cerebellum in the adult.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2_HUMAN; NTAK; Pro NRG2; Pro-NRG2

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