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Rabbit anti-Human NUDT6 Polyclonal Antibody

The antibody against NUDT6 was raised in rabbit using the Human NUDT6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-52509A

The antibody against NUDT6 was raised in rabbit using the Human NUDT6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-52509A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNUDT6
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NUDT6Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP53370
Background Information
  • Uniprot Id

    P53370

  • Target Species

    Human

  • Target Name

    NUDT6

  • Target Full Name

    Nucleoside diphosphate-linked moiety X motif 6

  • Target Function

    May contribute to the regulation of cell proliferation.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms.

  • Target Protein Families

    Nudix hydrolase family

  • Target Tissue Specificity

    Detected in liver, kidney and esophagus (at protein level). Ubiquitous.

  • Target Synonyms

    NUDT6; FGF2AS; Nucleoside diphosphate-linked moiety X motif 6; Nudix motif 6; EC 3.6.1.-; Antisense basic fibroblast growth factor; Protein GFG

  • Target Background

    This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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