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The antibody against NUP54 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human NUP54 (NP_059122.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NUP54 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human NUP54 (NP_059122.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05045A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUP54 |
| Target Synonyms | NUP54 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, LO2, Mouse lung, Mouse testis, Mouse thymus, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human NUP54 (NP_059122.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q7Z3B4 | Immunogen Sequence |
Uniprot Id
Q7Z3B4
Target Species
Human
Target Name
NUP54
Target Full Name
Nucleoporin p54
Target Function
Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane.
Target Subcellular Location
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side.
Target Protein Families
NUP54 family
Target Synonyms
54 kDa nucleoporin; MGC13407; Nucleoporin p54; Nup54; NUP54_HUMAN
Target Background
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset. Multiple alternatively spliced transcript variants have been found for this gene.
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