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The antibody against PGM1 was raised in rabbit using the Recombinant Human Phosphoglucomutase-1 protein (1-562AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PGM1 was raised in rabbit using the Recombinant Human Phosphoglucomutase-1 protein (1-562AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver cancer using PGM1 Antibody at dilution of 1:1002
| Cat.No | ADC-44523A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PGM1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphoglucomutase-1 protein (1-562AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P36871 |
Uniprot Id
P36871
Target Species
Human
Target Name
PGM1
Target Full Name
Phosphoglucomutase-1
Target Function
This enzyme participates in both the breakdown and synthesis of glucose.
Target Involvement
Congenital disorder of glycosylation 1T (CDG1T)
Target Subcellular Location
[Isoform 1]: Cytoplasm.
Target Protein Families
Phosphohexose mutase family
Target Research Area
Metabolism
Target Synonyms
CDG1T; Glucose phosphomutase 1; GSD14; OTTHUMP00000010519; OTTHUMP00000010520; PGM 1; PGM1; PGM1_HUMAN; Phosphoglucomutase 1; Phosphoglucomutase-1; Phosphoglucomutase1
Target Background
The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
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