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The antibody against PHACTR1 was raised in rabbit using the Recombinant Human Phosphatase and actin regulator 1 protein (263-387AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against PHACTR1 was raised in rabbit using the Recombinant Human Phosphatase and actin regulator 1 protein (263-387AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-05099A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PHACTR1 |
| Target Synonyms | PHACTR1 antibody; KIAA1733 antibody; RPEL1 antibody; Phosphatase and actin regulator 1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphatase and actin regulator 1 protein (263-387AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9C0D0 |
Uniprot Id
Q9C0D0
Target Species
Human
Target Name
PHACTR1
Target Full Name
Phosphatase and actin regulator 1
Target Function
Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity. Involved in the regulation of cortical neuron migration and dendrite arborization.
Target Subcellular Location
Cytoplasm. Cell junction, synapse. Nucleus.
Target Protein Families
Phosphatase and actin regulator family
Target Tissue Specificity
Detected in umbilical vein endothelial cells.
Target Synonyms
PHACTR1; KIAA1733; RPEL1; Phosphatase and actin regulator 1
Target Background
The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants.
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