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Rabbit anti-Human PLA2G4B Polyclonal Antibody

The antibody against PLA2G4B was raised in rabbit using the Recombinant Human Cytosolic phospholipase A2 beta protein (514-781AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-01631A

The antibody against PLA2G4B was raised in rabbit using the Recombinant Human Cytosolic phospholipase A2 beta protein (514-781AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-01631A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePLA2G4B
Target SynonymsPLA2G4B antibody; Cytosolic phospholipase A2 beta antibody; cPLA2-beta antibody; EC 3.1.1.4 antibody; Phospholipase A2 group IVB antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Cytosolic phospholipase A2 beta protein (514-781AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP0C869
Background Information
  • Uniprot Id

    P0C869

  • Target Species

    Human

  • Target Name

    PLA2G4B

  • Target Full Name

    Cytosolic phospholipase A2 beta

  • Target Function

    Calcium-dependent phospholipase A1 and A2 and lysophospholipase that may play a role in membrane phospholipid remodeling.; Calcium-dependent phospholipase A2 and lysophospholipase. Cleaves the ester bond of the fatty acyl group attached to the sn-2 position of phosphatidylethanolamines, producing lysophospholipids that may be used in deacylation-reacylation cycles. Hydrolyzes lysophosphatidylcholines with low efficiency but is inefficient toward phosphatidylcholines.; Calcium-dependent phospholipase A1 and A2 and lysophospholipase. Cleaves the ester bond of the fatty acyl group attached to the sn-1 or sn-2 position of diacyl phospholipids (phospholipase A1 and A2 activity, respectively), producing lysophospholipids that may be used in deacylation-reacylation cycles. Can further hydrolyze lysophospholipids enabling complete deacylation. Has no activity toward alkylacyl phospholipids.

  • Target Subcellular Location

    [Isoform 3]: Cytoplasm, cytosol. Mitochondrion membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein.; [Isoform 5]: Cytoplasm, cytosol.

  • Target Tissue Specificity

    Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas.

  • Target Synonyms

    PLA2G4B; Cytosolic phospholipase A2 beta; cPLA2-beta; EC 3.1.1.4; Phospholipase A2 group IVB

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