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The antibody against PLD2 was raised in rabbit using the Recombinant Human Phospholipase D2 protein (1-165AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against PLD2 was raised in rabbit using the Recombinant Human Phospholipase D2 protein (1-165AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human liver cancer using PLD2 Antibody at dilution of 1:100
| Cat.No | ADC-08430A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PLD2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phospholipase D2 protein (1-165AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14939 |
Uniprot Id
O14939
Target Species
Human
Target Name
PLD2
Target Full Name
Phospholipase D2
Target Function
Function as phospholipase selective for phosphatidylcholine. May have a role in signal-induced cytoskeletal regulation and/or endocytosis.
Target Subcellular Location
Cell membrane; Lipid-anchor.
Target Protein Families
Phospholipase D family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
Choline phosphatase 2; EC 3.1.4.4 ; hPLD 2; hPLD2; mPLD2; Phosphatidylcholine hydrolyzing phospholipase D2; Phosphatidylcholine-hydrolyzing phospholipase D2; Phospholipase D2; PhospholipaseD2; PLD 2; PLD1C; Pld2; PLD2_HUMAN; Pldc; rPLD2
Target Background
The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4, 5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.
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