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The antibody against PMS1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PMS1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against PMS1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PMS1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western Blot analysis of Jurkat cells using PMS1 Polyclonal Antibody
Western Blot analysis of various cells using PMS1 Polyclonal Antibody2
| Cat.No | ADC-37815A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PMS1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human PMS1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P54277 |
Uniprot Id
P54277
Target Species
Human
Target Name
PMS1
Target Full Name
PMS1 protein homolog 1
Target Function
Probably involved in the repair of mismatches in DNA.
Target Subcellular Location
Nucleus.
Target Protein Families
DNA mismatch repair MutL/HexB family
Target Synonyms
DNA mismatch repair protein PMS1; FLJ98259; HNPCC3; hPMS1; Human homolog of yeast mutL; Mismatch repair gene PMSL1; pms1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); PMS1 postmeiotic segregation increased 1; PMS1 protein homolog 1; PMS1_HUMAN; PMSL1; Rhabdomyosarcoma antigen MU RMS 40.10B; Rhabdomyosarcoma antigen MU RMS 40.10E
Target Background
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
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