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The antibody against PRMT9 was raised in rabbit using the Recombinant Human Putative protein arginine N-methyltransferase 9 protein (181-453AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against PRMT9 was raised in rabbit using the Recombinant Human Putative protein arginine N-methyltransferase 9 protein (181-453AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using PRMT9 Antibody at dilution of 1:100
| Cat.No | ADC-15295A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRMT9 |
| Target Synonyms | PRMT9 antibody; PRMT10 antibody; Protein arginine N-methyltransferase 9 antibody; Protein arginine N-methyltransferase 10 antibody; EC 2.1.1.320 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Putative protein arginine N-methyltransferase 9 protein (181-453AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6P2P2 |
Uniprot Id
Q6P2P2
Target Species
Human
Target Name
PRMT9
Target Full Name
Protein arginine N-methyltransferase 9
Target Function
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
Target Synonyms
PRMT9; PRMT10; Protein arginine N-methyltransferase 9; Protein arginine N-methyltransferase 10; EC 2.1.1.320
Target Background
This gene encodes a type II methyltransferase. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to the guanidino nitrogen atoms of arginine. The protein encoded by this gene methylates spliceosome associated protein 145 to regulate alternative splicing and acts as a modulator of small nuclear ribonucleoprotein maturation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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