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The antibody against PSKH1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PSK-H1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against PSKH1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PSK-H1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western Blot analysis of A549 cells using PSK-H1 Polyclonal Antibody
| Cat.No | ADC-37787A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PSKH1 |
| Target Synonyms | KPSH1_HUMAN antibody; Protein serine kinase H1 antibody; PSK H1 antibody; PSK-H1 antibody; PSKH1 antibody; Serine/threonine protein kinase H1 antibody; Serine/threonine-protein kinase H1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human PSK-H1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P11801 |
Uniprot Id
P11801
Target Species
Human
Target Name
PSKH1
Target Full Name
Serine/threonine-protein kinase H1
Target Function
May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing.
Target Subcellular Location
Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus speckle. Endoplasmic reticulum membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Cytoplasm. Note=Localized in the brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes.
Target Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Target Tissue Specificity
Expressed in all tissues and cell lines tested with the highest level of abundance in testis.
Target Synonyms
KPSH1_HUMAN; Protein serine kinase H1; PSK H1; PSK-H1; PSKH1; Serine/threonine protein kinase H1; Serine/threonine-protein kinase H1
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