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The antibody against PTH1R was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PTH/PTHrP-R. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against PTH1R was raised in rabbit using the Synthesized peptide derived from the Internal region of Human PTH/PTHrP-R. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of COLO cells using PTH/PTHrP-R Polyclonal Antibody
| Cat.No | ADC-34403A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTH1R |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human PTH/PTHrP-R. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q03431 |
Uniprot Id
Q03431
Target Species
Human
Target Name
PTH1R
Target Full Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
Target Function
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Target Involvement
Jansen metaphyseal chondrodysplasia (JMC); Chondrodysplasia Blomstrand type (BOCD); Enchondromatosis multiple (ENCHOM); Eiken skeletal dysplasia (EISD); Primary failure of tooth eruption (PFE)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family
Target Tissue Specificity
Expressed in most tissues. Most abundant in kidney, bone and liver.
Target Synonyms
PFE; EKNS; PTHR; PTHR1; PTH1R
Target Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
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