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The antibody against RAB12 was raised in rabbit using the Recombinant Human Ras-related protein Rab-12 protein (98-241AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against RAB12 was raised in rabbit using the Recombinant Human Ras-related protein Rab-12 protein (98-241AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-15307A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RAB12 |
| Target Synonyms | Putative Ras related protein Rab 12 antibody; RAB12 antibody; RAB12; member RAS oncogene family antibody; RAB12_HUMAN antibody; Ras-related protein Rab-12 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ras-related protein Rab-12 protein (98-241AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6IQ22 |
Uniprot Id
Q6IQ22
Target Species
Human
Target Name
RAB12
Target Full Name
Ras-related protein Rab-12
Target Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy.
Target Subcellular Location
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Lysosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome.
Target Protein Families
Small GTPase superfamily, Rab family
Target Research Area
Neuroscience
Target Synonyms
Putative Ras related protein Rab 12; RAB12; RAB12; member RAS oncogene family; RAB12_HUMAN; Ras-related protein Rab-12
Target Background
Enables GDP binding activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; endosome to lysosome transport; and secretion by cell. Predicted to act upstream of or within cellular response to interferon-gamma. Predicted to be located in lysosome; phagocytic vesicle; and recycling endosome membrane. Predicted to be active in Golgi apparatus; cytoplasmic vesicle; and plasma membrane.
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