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Rabbit anti-Human RAB20 Polyclonal Antibody

The antibody against RAB20 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-190 of human RAB20 (NP_060287.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-07051A

The antibody against RAB20 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-190 of human RAB20 (NP_060287.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-07051A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRAB20
Target SynonymsRAB20FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heartApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 80-190 of human RAB20 (NP_060287.1).Target SpeciesHuman
Immunogen SequenceYDVNHRQSLVELEDRFLGLTDTASKDCLFAIVGNKVDLTEEGALAGQEKEECSPNMDAGDRVSPRAPKQVQLEDAVALYKKILKYKMLDEQDVPAAEQMCFETSAKTGYNVUniprot IDQ9NX57
Background Information
  • Uniprot Id

    Q9NX57

  • Target Species

    Human

  • Target Name

    RAB20

  • Target Full Name

    Ras-related protein Rab-20

  • Target Function

    Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.

  • Target Subcellular Location

    Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side.

  • Target Protein Families

    Small GTPase superfamily, Rab family

  • Target Tissue Specificity

    Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).

  • Target Synonyms

    FLJ20429; RAB20; RAB20 member RAS oncogene family; RAB20_HUMAN; Ras related protein Rab20; Ras-related protein Rab-20

  • Target Background

    Predicted to enable GTPase activity. Involved in phagosome acidification and phagosome-lysosome fusion. Located in Golgi apparatus and phagocytic vesicle.

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