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The antibody against RASEF was raised in rabbit using the Human RASEF as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against RASEF was raised in rabbit using the Human RASEF as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47407A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RASEF |
| Target Synonyms | RASEF antibody; RAB45 antibody; Ras and EF-hand domain-containing protein antibody; Ras-related protein Rab-45 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human RASEF | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IZ41 |
Uniprot Id
Q8IZ41
Target Species
Human
Target Name
RASEF
Target Full Name
Ras and EF-hand domain-containing protein
Target Function
Binds predominantly GDP, and also GTP. Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules.
Target Subcellular Location
Cytoplasm, perinuclear region.
Target Protein Families
Small GTPase superfamily, Rab family
Target Tissue Specificity
Down-regulated in cutaneous melanoma cells but not in breast cancer cells.
Target Synonyms
RASEF; RAB45; Ras and EF-hand domain-containing protein; Ras-related protein Rab-45
Target Background
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene.
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