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The antibody against RIOK1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human RIOK1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against RIOK1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human RIOK1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-33618A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIOK1 |
| Target Synonyms | AD034 antibody; bA288G3.1 antibody; RIO kinase 1 (yeast) antibody; RIO kinase 1 antibody; RIOK1 antibody; RIOK1_HUMAN antibody; Serine/threonine-protein kinase rio1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human RIOK1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BRS2 |
Uniprot Id
Q9BRS2
Target Species
Human
Target Name
RIOK1
Target Full Name
Serine/threonine-protein kinase RIO1
Target Function
Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation.
Target Subcellular Location
Cytoplasm, cytosol.
Target Protein Families
Protein kinase superfamily, RIO-type Ser/Thr kinase family
Target Synonyms
AD034; bA288G3.1; RIO kinase 1 (yeast); RIO kinase 1; RIOK1; RIOK1_HUMAN; Serine/threonine-protein kinase rio1
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