Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against RIT1 was raised in rabbit using the Recombinant Human GTP-binding protein Rit1 protein (1-219AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RIT1 was raised in rabbit using the Recombinant Human GTP-binding protein Rit1 protein (1-219AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using RIT1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human thyroid tissue using RIT1 Antibody at dilution of 1:1002
| Cat.No | ADC-18764A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIT1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human GTP-binding protein Rit1 protein (1-219AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92963 |
Uniprot Id
Q92963
Target Species
Human
Target Name
RIT1
Target Full Name
GTP-binding protein Rit1
Target Function
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.
Target Involvement
Noonan syndrome 8 (NS8)
Target Subcellular Location
Cell membrane.
Target Protein Families
Small GTPase superfamily, Ras family
Target Tissue Specificity
Expressed in many tissues.
Target Synonyms
GTP binding protein Roc1; GTP-binding protein Rit1; NS8; Ras like protein expressed in many tissues; Ras like without CAAX 1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; Ric like expressed in many tissues; Ric-like protein without CAAX motif 1; RIT; RIT1; RIT1_HUMAN; ROC1
Target Background
This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
