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The antibody against RND3 was raised in rabbit using the Human RND3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against RND3 was raised in rabbit using the Human RND3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-47342A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RND3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human RND3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P61587 |
Uniprot Id
P61587
Target Species
Human
Target Name
RND3
Target Full Name
Rho-related GTP-binding protein RhoE
Target Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Target Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein.
Target Protein Families
Small GTPase superfamily, Rho family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
ARHE; memB; Protein MemB; Ras homolog gene family member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rho8; RhoE; Rnd3; RND3_HUMAN; Small GTP binding protein Rho8
Target Background
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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