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The antibody against RTN2 was raised in rabbit using the Human RTN2 as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on ELISA, WB.
The antibody against RTN2 was raised in rabbit using the Human RTN2 as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47287A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RTN2 |
| Target Synonyms | RTN2; NSPL1; Reticulon-2; Neuroendocrine-specific protein-like 1; NSP-like protein 1; Neuroendocrine-specific protein-like I; NSP-like protein I; NSPLI | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human RTN2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75298 |
Uniprot Id
O75298
Target Species
Human
Target Name
RTN2
Target Full Name
Reticulon-2
Target Function
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. Enhances trafficking of the glutamate transporter SLC1A1/EAAC1 from the endoplasmic reticulum to the cell surface. Plays a role in the translocation of SLC2A4/GLUT4 from intracellular membranes to the cell membrane which facilitates the uptake of glucose into the cell.
Target Involvement
Spastic paraplegia 12, autosomal dominant (SPG12)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane, sarcolemma, T-tubule; Multi-pass membrane protein. Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, cytoskeleton.
Target Tissue Specificity
[Isoform RTN2-C]: Highly expressed in skeletal muscle.
Target Synonyms
RTN2; NSPL1; Reticulon-2; Neuroendocrine-specific protein-like 1; NSP-like protein 1; Neuroendocrine-specific protein-like I; NSP-like protein I; NSPLI
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