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Rabbit anti-Human S100A5 Polyclonal Antibody

The antibody against S100A5 was raised in rabbit using the Synthesized peptide derived from internal of Human S100A5. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41007A

The antibody against S100A5 was raised in rabbit using the Synthesized peptide derived from internal of Human S100A5. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41007A ClonalityPolyclonal
Host SpeciesRabbitTarget NameS100A5
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human S100A5.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP33763
Background Information
  • Uniprot Id

    P33763

  • Target Species

    Human

  • Target Name

    S100A5

  • Target Full Name

    Protein S100-A5

  • Target Function

    Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites.

  • Target Protein Families

    S-100 family

  • Target Synonyms

    Protein S-100D; Protein S100-A5; S100 calcium binding protein A5; S100 calcium-binding protein A5; S100a5; S100D; S100D9; S10A5_HUMAN

  • Target Background

    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain.

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