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The antibody against SAP130 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SAP130 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00686A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SAP130 |
| Target Synonyms | SAP130 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H0E3 | Immunogen Sequence |
Uniprot Id
Q9H0E3
Target Species
Human
Target Name
SAP130
Target Full Name
Histone deacetylase complex subunit SAP130
Target Function
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.
Target Subcellular Location
Nucleus.
Target Protein Families
SAP130 family
Target Tissue Specificity
Expressed in various cancer cell ines.
Target Synonyms
130 kDa Sin3-associated polypeptide; FLJ12761; Histone deacetylase complex subunit SAP130; mSin3A associated protein 130; Sap130; Sin3-associated polypeptide p130; Sin3A associated protein 130kDa; Sin3A associated protein; SP130_HUMAN
Target Background
SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).
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