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The antibody against SCN4B was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Scn4b. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against SCN4B was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Scn4b. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western Blot analysis of?HepG2 cells using Scn4b Polyclonal Antibody
| Cat.No | ADC-37648A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCN4B |
| Target Synonyms | SCN4B antibody; Sodium channel subunit beta-4 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Scn4b. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IWT1 |
Uniprot Id
Q8IWT1
Target Species
Human
Target Name
SCN4B
Target Full Name
Sodium channel regulatory subunit beta-4
Target Function
Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.
Target Involvement
Long QT syndrome 10 (LQT10); Atrial fibrillation, familial, 17 (ATFB17)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Sodium channel auxiliary subunit SCN4B (TC 8.A.17) family
Target Tissue Specificity
Expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Expressed in the atrium.
Target Synonyms
SCN4B; Sodium channel subunit beta-4
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