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The antibody against SH3D19 was raised in rabbit using the Recombinant Human SH3 domain-containing protein 19 protein (468-767AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SH3D19 was raised in rabbit using the Recombinant Human SH3 domain-containing protein 19 protein (468-767AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using SH3D19 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using SH3D19 Antibody at dilution of 1:1002
| Cat.No | ADC-19971A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SH3D19 |
| Target Synonyms | SH3D19 antibody; SH3 domain-containing protein 19 antibody; ADAM-binding protein Eve-1 antibody; EEN-binding protein antibody; EBP antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human SH3 domain-containing protein 19 protein (468-767AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5HYK7 |
Uniprot Id
Q5HYK7
Target Species
Human
Target Name
SH3D19
Target Full Name
SH3 domain-containing protein 19
Target Function
May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.
Target Tissue Specificity
Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes.
Target Synonyms
SH3D19; SH3 domain-containing protein 19; ADAM-binding protein Eve-1; EEN-binding protein; EBP
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