Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SIGIRR was raised in rabbit using the Recombinant Human Single Ig IL-1-related receptor protein (1-120AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against SIGIRR was raised in rabbit using the Recombinant Human Single Ig IL-1-related receptor protein (1-120AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver cancer using SIGIRR Antibody at dilution of 1:1002
| Cat.No | ADC-16438A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SIGIRR |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Single Ig IL-1-related receptor protein (1-120AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6IA17 |
Uniprot Id
Q6IA17
Target Species
Human
Target Name
SIGIRR
Target Full Name
Single Ig IL-1-related receptor
Target Function
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
Target Subcellular Location
Membrane; Single-pass type III membrane protein.
Target Protein Families
Interleukin-1 receptor family
Target Tissue Specificity
Mainly expressed in epithelial tissues such as kidney, lung and gut.
Target Research Area
Immunology
Target Synonyms
Ig IL1 related receptor; MGC110992; SIGIR_HUMAN; SIGIRR; Single Ig IL 1 related receptor; Single Ig IL-1-related receptor; Single Ig IL-1R-related molecule; Single Ig IL1R Related Molecule; Single immunoglobulin and toll interleukin 1 receptor (TIR) domain; Single immunoglobulin and toll interleukin 1 receptor domain; Single immunoglobulin domain containing IL1R related protein; Single immunoglobulin domain IL1R1 related; Single immunoglobulin domain-containing IL1R-related protein; TIR 8; TIR8; Toll/interleukin 1 receptor 8; Toll/interleukin-1 receptor 8
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
