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The antibody against SLC24A1 was raised in rabbit using the Recombinant Human Sodium/potassium/calcium exchanger 1 protein (330-452AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SLC24A1 was raised in rabbit using the Recombinant Human Sodium/potassium/calcium exchanger 1 protein (330-452AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human brain tissue using SLC24A1 Antibody at dilution of 1:100
| Cat.No | ADC-16430A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC24A1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Sodium/potassium/calcium exchanger 1 protein (330-452AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60721 |
Uniprot Id
O60721
Target Species
Human
Target Name
SLC24A1
Target Full Name
Sodium/potassium/calcium exchanger 1
Target Function
Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Target Involvement
Night blindness, congenital stationary, 1D (CSNB1D)
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family, SLC24A subfamily
Target Tissue Specificity
Expressed in the retina, particularly in the inner segment, outer and inner nuclear layers, and ganglion cell layer.
Target Synonyms
CSNB1D; HsT17412; KIAA0702; Na(+)/K(+)/Ca(2+) exchange protein 1; Na(+)/K(+)/Ca(2+)-exchange protein 1; NCKX; NCKX1; NCKX1_HUMAN; Retinal rod Na Ca+K exchanger; Retinal rod Na+/Ca+/K+ exchanger; Retinal rod Na-Ca+K exchanger; RODX; Slc24a1; Sodium/potassium/calcium exchanger 1; Solute carrier family 24 (sodium/potassium/calcium exchanger) member 1; Solute carrier family 24 member 1
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