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The antibody against SLC3A1 was raised in rabbit using the Recombinant Human Neutral and basic amino acid transport protein rBAT protein (1-68AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against SLC3A1 was raised in rabbit using the Recombinant Human Neutral and basic amino acid transport protein rBAT protein (1-68AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-10360A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC3A1 |
| Target Synonyms | +)-type amino acid transport protein antibody; amino acid transporter 1 antibody; ATR1 antibody; B(0 antibody; B(0 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Neutral and basic amino acid transport protein rBAT protein (1-68AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q07837 |
Uniprot Id
Q07837
Target Species
Human
Target Name
SLC3A1
Target Full Name
Amino acid transporter heavy chain SLC3A1
Target Function
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.
Target Involvement
Cystinuria (CSNU); Hypotonia-cystinuria syndrome (HCS)
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Tissue Specificity
Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver.
Target Synonyms
D2H; ATR1; NBAT; RBAT; CSNU1; SLC3A1
Target Background
This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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