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The antibody against SLITRK4 was raised in rabbit using the Recombinant Human SLIT and NTRK-like protein 4 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SLITRK4 was raised in rabbit using the Recombinant Human SLIT and NTRK-like protein 4 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using SLITRK4 Antibody at dilution of 1:100
| Cat.No | ADC-19248A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLITRK4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human SLIT and NTRK-like protein 4 protein (201-500AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IW52 |
Uniprot Id
Q8IW52
Target Species
Human
Target Name
SLITRK4
Target Full Name
SLIT and NTRK-like protein 4
Target Function
It is involved in synaptogenesis and promotes synapse differentiation. Suppresses neurite outgrowth.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Cell membrane.
Target Protein Families
SLITRK family
Target Tissue Specificity
Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors.
Target Synonyms
SLITRK4
Target Background
This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants.
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