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Rabbit anti-Human SLITRK4 Polyclonal Antibody

The antibody against SLITRK4 was raised in rabbit using the Human SLITRK4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47133A

The antibody against SLITRK4 was raised in rabbit using the Human SLITRK4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-47133A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSLITRK4
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman SLITRK4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8IW52
Background Information
  • Uniprot Id

    Q8IW52

  • Target Species

    Human

  • Target Name

    SLITRK4

  • Target Full Name

    SLIT and NTRK-like protein 4

  • Target Function

    It is involved in synaptogenesis and promotes synapse differentiation. Suppresses neurite outgrowth.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein. Cell membrane.

  • Target Protein Families

    SLITRK family

  • Target Tissue Specificity

    Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors.

  • Target Synonyms

    SLITRK4

  • Target Background

    This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants.

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